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PROTEIN C
Descriptors Found:
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DeCS
Descriptor
English
:
Protein C
Descriptor
Spanish
:
Proteína C
Descriptor
Portuguese
:
Proteína C
Tree Number:
D08.622.705
D12.776.124.650
D12.776.395.635
D23.113.700
Definition
English
:
A vitamin-K dependent zymogen present in the
blood
, which, upon activation by
thrombin
and
thrombomodulin
exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of
thrombin
formation.
Pharmacological Action:
Anticoagulants
Fibrinolytic Agents
Entry Combination - descr/qualif
English
:
Protein C
/
deficiency
use
Protein C Deficiency
History Note
English
:
87
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
22311
Unique Identifier:
D011486
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS